Biothintank Spa

most relevant achievements • pioneers in developing, patenting, and commercialization of unique technologies for the extraction, purification, and fractionation of histones, preserving histone’s original biomarkers. the isolated histones are used in epigenetic research, drug-development and testing, clinical diagnosis, and biomanufacturing of biologicals. the technological know-hows were transferred to active motif, a north american company that markets them. • pioneers in the invention of a universal detection method, with imidazole-zinc salts (im-zn), for the ultra-detection and identification of proteins and polymers, in polyacrylamide gels. im-zn was one of the first methods invented that does not alter the chemical nature of proteins, allowing their subsequent identification by mass spectrometry and immunological techniques. • pioneers in cloning the streptokinase from streptococcus equisimilis, using the recombinant protein (rsk), for the first time, in the clinical treatment