Black Pearl Therapeutics Sa

black pearl therapeutics (bptx) is an emerging biotech focused on the discovery and development of novel precision medicines for rare diseases with strong unmet need. leveraging on our proprietary ai platform sirius ai we unveil overlooked molecular targets and molecular entities active on those targets that we then further develop and optimize into drug candidates, sensibly reducing the lead optimization time. combining outputs from sirius ai with the internal know-how, specifically computational, medicinal chemistry and translational pharmacology excellence, we have identified potential first-in-class therapies to address the core of severe renal (alport syndrome) and autoimmune (anca vasculitis) rare diseases. - in alport syndrome, we designed a library of compounds active on a specific receptor over-expressed in these patients, aiming at achieving renal protection through preventing the growth of fibrotic tissue. preliminary poc data in vivo confirmed our hypothesis and additiona