Ipromedai - Improved Protection of Medical Devices Against Infection

device-associated infection (dai) constitutes one of the key reasons for clinical failure, impaired functionality, and reduced lifetime of medical devices, resulting in high distress for the patients and huge socioeconomic costs. the prime objective of this action is the identification and assessment of recently developed anti-dai approaches in a comprehensive pan-european effort. understanding and combating dai is a device-dependent, highly complex and transdisciplinary challenge requiring collaborations between clinics to define the practical boundary conditions and unmet needs, material and surface engineering to elaborate on enhanced material/drug combination systems, pharmacology and (micro)biology to explore novel antimicrobial active compounds and establish advanced, dai-relevant test systems in vitro as well as in dedicated animal models. the most promising concepts and engineered prototypic devices are finally evaluated in a preclinical setting. action members from the medical